Causes of prostatitis

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Stoyanov
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Causes of prostatitis

#1 Post by Stoyanov » 30 Apr 2018, 15:17

Progression of inflammation in the prostate is determined by pathogenic or conditionally pathogenic microbes entering the organ. Chronic prostatitis is provoked by bacteria such as Escherichia coli (which is detected in 75-80% of patients with chronic bacterial prostatitis), Enterobacteria, Proteus, Pseudomonas, Klebsiella, Enterobacter, Enterococcus faecalis, Serratia. Approximately 20% of patients show simultaneously two or more varieties of pathogenic microorganisms.

It is not exactly known whether pathogens of sexually transmitted infections (STDs) can be the direct cause of prostatitis, but the fact that their presence is a serious risk factor for inflammation of the body is indisputable. The most recent studies show the relationship between chronic prostatitis and infection with chlamydia, trichomonas, and ureaplasma.

Main Routes of Infection:
• as a result of urethral content and/or urinary reflux caused by urea-prostatic reflux;
• against the background of urethritis, infection is introduced mainly with pathogens that are transmitted sexually, viz. with gonococci, chlamydia, or less frequently, if local antibacterial protection is violated is possible by gonococci, chlamydia, or less frequently, if local antibacterial protection is violated, with myco- and ureaplasma, and other bacterial agents (upon anal-genital contact – by intestinal agents, upon genital-oral contact – by respiratory ones), herpes virus, cytomegalovirus, or yeast fungi;
• via deferent ducts (relatively rare), when affected by vesiculitis and/or orchiepididymitis, the infection penetrates from the testes, seminal vesicles, and appendages;
• extremely rare (which even causes doubts in a number of doctors), affected by pyelonephritis, cystitis, glomerulonephritis through urine containing infectious agents;
• when carried from other systems/organs through the lymphatic or blood vessels.

Factors Contributing to Advanced Inflammation of the Prostate:
• failure in the urethral antimicrobial barrier (due to damage to the urethral mucosa, for example, in gonorrhea or chlamydia);
• impaired blood microcirculation, which leads to a reduced supply of prostate with vital products and an increase in the local temperature favorable for the propagation of pathogenic microbes (the problem may be caused by varicose, hemorrhoids, alcoholic or nicotine intoxication, neurogenic disorders, insufficient physical activity);
• hormonal disorders (lowering the testosterone level leads to a decrease in the production of the prostatic secretion and worsening of the antimicrobial function of the gland).

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